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X-ray technique opens door to nanoscale biological insights

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A study published this week in Science demonstrates the potential of free-electron lasers (FEL) to obtain high-resolution structural insight into macromolecules. An international team of researchers determined the structure of hen egg white lysozyme down to a resolution of 0.19 nanometers. Despite the intensity of FEL X-ray pulses, which destroy the sample, the method delivers high quality structural data. "The exceptionally intense X-ray pulses possible with FELs open the door for...

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